Risk of Rain (1) is decent as far as I remember, although the controls need some getting into.
Enter the Gungeon is excellent from what I've heard, although fast paced, haven't played it myself though.
I played The Binding of Isaac:Rebirth for like 1000 hours, it's mechanically the best roguelike out there imo, but it's extremely vulgar and has a lot of satanic themes. Like you can sacrifice HP to get strong devil items, but if you don't take them you'll maybe get an angel room and get more powerful items for free. But it's interesting in that you play as a 3 year old boy that is fleeing into the basement from his single mom that watches evangelical tv and wants to kill him because she thinks God is telling her to do that. It has some themes that could be interpreted as anti-christian, but at the same time there are end-bosses like The Beast and Mega Satan. It's actually interesting, I've also played the earlier flash version of the game(like 10 years ago), and the anti-christian themes actually diminished over time. The designer of the game, Edmund McMillen, said the game is an expression of his childhood, he grew up in a catholic household with a single mother that was heavily influenced by american evangelical television. A main theme of the game is that Isaac(the protagonist), starts to hate himself because his mother starts being abusive towards him after the father leaves, and he becomes convinced that he has a demon inside him and was responsible for the bad things happening in his family. But McMillen said himself, that his hatred of christianity caused by his childhood went away because he later realized that the mistreatings that he was subject to were not a product of the faith, but of his broken home. Although as far as I know, he still isn't a christian. Again, I'd still not advise to play the game, because it's extremely vulgar(piss and shit in the form of enemies and items are a common theme, although it is presented in a very comical and pixelated style, and there's nothing sexual), but I think the history behind the game is really interesting. Maybe I'll make a more detailed thread about it at some point.